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How to use/store:
Composition and Product Description:
The product is manufactured by Medytox Inc. in the form of a solution in vials, one in a package. The basic component is botulotoxin type A Clostridium botulinum in the amount of 50 units.
Innotox is predicted by the same Hall strain of C.botulinum as Neuronox and Botox. The molecular weight of Innotox analyzed using size exclusion SE-HPLC is approximately 900 kDa. Which is highly comparable to those of Neuronox and Botox.
Another key characteristic of Innotox is that it excludes the use of substances of animal origin in the manufacturing process to eliminate the risks associated with animal-based proteins. Moreover, it excludes human serum albumin as an excipient of the final product to avoid any risk associated with diseases of human blood origin. Instead it contains methionine and polysorbate as a stabilizer.
The safety and efficacy of Innotox and Botox were compared at a 1:1 dose ratio for treating glabellar lines in a double-blinded, randomized, phase III multi center study with 168 subjects. The patients, aged 20 to 65 years with moderate-to-severe glabellar lines, were randomly treated with 20U of Innotox or Botox and subsequently assessed by blinded investigators. The improvement rate at both maximum frown and rest was not significantly different between the Innotox and Botox groups. No severe adverse drug reactions were observed.
With these advantages, Allergan, the Botox manufacturer, made an exclusive license agreement to market Innotox worldwide, excluding Korea and Japan.